The Project host Lisa Wilkinson will quit the show after what she says has been six months of toxic media that have affected not only her but her loved ones.
Wilkinson ran into trouble after some comments she made about her interview with Brittany Higgins at the Logies Awards.
Tracy Grimshaw also leaves A Current Affair this week.
In the United States, the first woman to lead the US House, Nancy Pelosi, has also given notice that she is stepping down.